Self-assembled
structures from microgel particles using microfluidics
Microgel
particles are cross-linked latex particles that swell in appropriate
solvents. They are extensively used in
the surface coating industry and are being researched for applications in the
printing, pharmaceutical and cosmetics industries [1]. Their ability to swell/ de-swell in response
to changes in pH, temperature, or other stimuli makes them interesting
candidates for targeted release applications.
This
study is geared towards the fabrication of novel self-assembled structures from
microgel particles using microfluidic
devices. The use of capillary based microfluidic devices allows us to create monodisperse droplets [2] which should help us gain precise
control over the release kinetics. We
intend to develop a better understanding of the physics behind the
self-organization of such structures and their properties.
Preliminary results:
Single emulsion using a microcapillary device
Monodisperse droplets of an aqueous microgel
solution in oil (bulk phase) and their crumpled morphology after drying.
References:
[1] B. R. Saunders, B.
Vincent, Advances in colloid and interface science 80 1-25 (1999).
[2] A. S. Utada,
E. Lorenceau, D. R. Link, P. D. Kaplan, H. A. Stone,
D. A. Weitz, Science 308 537–541 (2005).
________________________________________________________________
Contact:
Rhutesh Shah
Division of Engineering and
Applied Sciences (DEAS)
Phone: 617-384-5950
Email:
rhutesh@deas.harvard.edu