John L. Loeb Associate Professor of the Natural Sciences and Associate Professor of Electrical Engineering
Donhee Ham is John L. Loeb Associate Professor of the Natural Sciences and Associate Professor of Electrical Engineering at Harvard University, where he is with the School of Engineering and Applied Sciences (Programs: Electrical Engineering and Applied Physics).
Donhee Ham's work experiences include Caltech-MIT Laser Interferometer Gravitational Wave Observatory (LIGO), IBM T. J. Watson Research Center, IEEE conference technical program committees including the IEEE International Solid-State Circuits Conference (ISSCC) and the IEEE Asian Solid-State Circuits Conference (ASSCC), advisory board for the IEEE International Symposium on Circuits and Systems (ISCAS), international advisory board for the Institute for Nanodevice and Biosystems, and various US, Korea, and Japan industry, government, & academic technical advisory positions on subjects including ultrafast electronics, science & technology at the nanoscale, and the interface between biotechnology and microelectronics. He is serving as a guest editor for the IEEE Journal of Solid-State Circuits, (JSSC) and is a co-editor of CMOS Biotechnology with Springer (2007).
Ham's current research focus is on (1) RF/microwave, analog & mixed-signal ICs, (2) ultrafast 1-dimensional electron transport, (3) soliton electronics, (4) applications of CMOS ICs in biotechnology, and (5) nonequilibrium statistical physics of electrical circuits. At Harvard University, Donhee Ham works with a group of talented electrical engineering and applied physics students, which include top rankers in top universities worldwide, US intercollegiate science competitions, and international science competitions.
Dr. Donald E. Ingber
Judah Folkman Professor of Vascular Biology in the Department of Pathology, Harvard Medical School
Dr. Ingber is the first incumbent of the Judah Folkman Professorship of Vascular Biology in the Department of Pathology at Harvard Medical School, and a member of the Pathology, Surgery and Vascular Biology Programs at Children¹s Hospital Boston.
He is also the Director and Core Faculty Member of the
Wyss Institute for Biologically Inspired Engineering at Harvard University. He has helped to bridge the Harvard hospitals, Harvard University and MIT through his involvement in the Center for Integration in Medicine and Innovative Technology (CIMIT), Harvard-MIT Health Science & Technology Division and Dana Farber-Harvard Cancer Center. He is also a member of the Center for Nanoscale Systems and the Materials Research Science & Engineering Center at Harvard, as well as the MIT Center for Bioengineering.
Ingber has authored 260 publications and 30 patents in areas ranging from tissue engineering, medical microdevices, and nanotechnologies to anti-angiogenic therapeutics and computer software. Ingber's theoretical and experimental contributions have led to honors in medical science, anatomy, developmental biology, mechanical engineering, and theoretical mechanics from leading institutions including the Mayo Clinic, Stanford, and MIT as well as recognition by NASA and the American Cancer Society. He also helped to found two biotechnology start-ups, and has consulted for multiple pharmaceutical, biotechnology, venture capital and private investment companies, as well as National Public Radio, the Department of Defense and the Office of National Intelligence. Through his interdisciplinary collaborations with experts in chemistry, physics, engineering, magnetics and optics, Ingber has helped to develop multiple new experimental nano- and microtechnologies, as well as engineered tissues and angiogenesis inhibitor-based cancer therapeutics that have entered human clinical trials. His pioneering work has led to the discovery of fundamental design principles that govern how molecules are structured into living cells, as well as how cells are integrated within tissues and organs, that have helped to birth the fields of Mechanobiology, Angiogenesis, Tissue Engineering, Nanobiotechnology, and Biomimetics.
Charles M. Lieber
Mark Hyman, Jr. Professor of Chemistry
Charles Lieber conducted his doctoral studies at Stanford University and postdoctoral research at the California Institute of Technology, he moved to the East Coast in 1987 to assume a position of Assistant Professor at Columbia University. Here Lieber embarked upon a new research program addressing the synthesis and properties of low-dimensional materials. He moved to Harvard University in 1991 and now holds a joint appointment in the Department of Chemistry and Chemical Biology, as the Mark Hyman Professor of Chemistry, and the School of Engineering and Applied Sciences. At Harvard, Lieber has pioneered the synthesis of a broad range of nanoscale materials, the characterization of the unique physical properties of these materials and the development of methods of hierarchical assembly of nanoscale wires, together with the demonstration of applications of these materials in nanoelectronics, nanocomputing, biological and chemical sensing, neurobiology and nanophotonics. Lieber has also developed and applied a new chemically sensitive microscopy for probing organic and biological materials at nanometer to molecular scales. His work has been recognized by a number of awards, including the Einstein Award, Chinese Academy of Sciences (2008); NBIC Research Excellence Award, University of Pennsylvania (2007); Nanotech Briefs Nano 50 Award (2005); ACS Award in the Chemistry of Materials (2004); World Technology Award in Materials (2004 and 2003); Scientific American 50 Award in Nanotechnology and Molecular Electronics (2003); New York Intellectual Property Law Association Inventor of the Year (2003); APS McGroddy Prize for New Materials (2003); Harrison Howe Award, University of Rochester (2002); MRS Medal (2002); Feynman Prize in Nanotechnology (2001); NSF Creativity Award (1996) and ACS Award in Pure Chemistry (1992). Lieber is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences, Fellow of the Materials Research Society, American Physical Society, Institute of Physics and American Association for the Advancement of Science. Lieber is Co-Editor of Nano Letters, and serves on the Editorial and Advisory Boards of a large number of science and technology journals. He also serves on the Technology Advisory Committee of Samsung Electronics. Lieber has published more than 300 papers in peer-reviewed journals and is the principal inventor on more than 35 patents. In his spare time, Lieber has been active in commercializing nanotechnology, and has founded the nanotechnology companies: Nanosys, Inc. in 2001 and the new nanosensor company Vista Therapeutics in 2007.
Fellow, Rowland Institute at Harvard
Frank Vollmer is the principal investigator of the Biofunctional Photonics Group at the Rowland Institute at Harvard where he holds the position of Rowland Junior Fellow. He received his M.S. in Biochemistry in 1998, and his Ph.D. in ‘Physics in Biology’ from The Rockefeller University, New York, in 2004. For his master thesis he worked in Dr. Robert Roeder's Laboratory of Biochemistry on the characterization of an eukaryotic transcription factor. His Ph.D. thesis was supervised by Dr. Albert Libchaber: the work in experimental physics concerned perturbations of high-Q optical microcavities with nanoparticles and biomolecules for detection and analysis. He received a scholarship from the Boehringer Ingelheim Fonds, Germany.
Mallinckrodt Professor of Applied Physics and of Physics
Robert Westervelt received his Ph.D. from the University of California, Berkeley in 1977. Following a postdoctoral appointment at Berkeley, he moved to Harvard University, where he is currently Mallinckrodt Professor of Applied Physics & Physics, and Professor of Physics. He is a Fellow of the American Physical Society.
Professor Westervelt's group investigates the quantum behavior of electrons inside nanoscale semiconductor structures, and develops tools for the manipulation of biological systems. In mesoscopic physics, the group has developed liquid-helium cooled scanning probe microscopes that can image electron motion through nanoscale devices. They visualized the flow of electron waves through a two-dimensional electron gas (Topinka et al. 2003) and observed diffraction patterns and coherent interference (LeRoy et al. 2005), as well as cyclotron orbits in a magnetic field (Aidala et al. 2007). They have used the conducting tip as a movable gate to control a one-electron quantum dot formed in a semiconductor nanowire (Bleszynski et al. 2008) and a GaAs heterostructure (Fallahi et al. 2005). In related research, they have developed tunnel-coupled quantum dots and studied their behavior as artificial molecules (Livermore et al. 2006, Vidan et al. 2006) and tested Josephson junctions formed in Ge/Si nanowires (Xiang et al. 2006).
On the biophysics side, Westervelt's group has developed hybrid Integrated Circuit / Microfluidic chips that combine the power of CMOS technology with the biocompatibility of microfluidics (Lee, Ham & Westervelt, 2007, Hunt et al. 2008). These devices act as programmable microfluidic systems that can trap, move, sort, and assemble biological cells and small particles in fluids.
Robert Westervelt is Director of the NSF-funded Nanoscale Science and Engineering Center, Science of Nanoscale Systems and their Device Applications, which is basedat Harvard University and includes participants at MIT, UC Santa Barbara and the Museum of Science, Boston. Previously Westervelt served as Director of the Materials Research Science and Engineering Center and as Co-Director of the Joint Services Electronics Program, both at Harvard.
Woodford L. and Ann A. Flowers University Professor
George M. Whitesides is the Woodford L. and Ann A. Flowers University Professor. Professor Whitesides and his group work in four areas: biochemistry, materials science, catalysis and physical organic chemistry. Each of these areas requires development of the fundamental skills of experimental chemistry - synthesis and characterization of new compounds, examination of relations between molecular structure and reactivity or physical properties—but each, in addition, develops skill in other techniques—surface spectroscopy, microbiology, electron microscopy, ellipsometry, reactor design, measurement of such physical properties. The group is eclectic and generalist in its approach: at different times research on a particular problem may require organic synthesis, organometallic chemistry, spectroscopy, computer analysis, biochemistry, molecular biology or a wide range of other techniques. The specific foci of the research vary widely. Work in biochemistry currently centers on adhesion of mammalian cells, viruses and bacteria to surfaces, polyvalency, rational drug design, and biophysical studies centered around capillary electrophoresis and surface plasmon resonance spectroscopy. Those coworkers concerned with materials science are occupied with the fabrication of nanostructures, microfluidic systems, microelectromechanical systems, and 3-D microstructures. The synthesis and characterization of structurally well-defined organic surfaces (especially using self-assembled monolayers) and solids, and the use of these assemblies to study physical properties such as wettability and biocompatibility, are an important component of this work. This area also includes studies in physical optics and unconventional methods of lithography (soft lithography; various forms of near-field optical lithography). Much of the work in catalysis centers on fuel cells. Problems in physical-organic chemistry address issues in self-assembly, especially using meso-scale systems (objects with dimensions from 10 μm—10 mm, held together by capillary and/or magnetic forces). Computation and simulation are also important tools in the group. The group uses classical chemical techniques to work in areas of research that lie at the boundaries between chemistry and biology, catalysis, solid state physics, and engineering. Students who work in the group emerge as generalists, and there is a strong emphasis in learning how to carry out multidisciplinary and multi-investigator research, and how to communicate the results of research effectively.
Professor of Physics
Professor Yacoby is an experimental condensed matter physicist at Harvard University in the Department of Physics. He received his PhD from the Weizmann Institute of Science in 1994, and researched at Bell Labs in Murray Hill before joining the faculty at the Weizmann Institute where he remained until 2006.
His current research interests are focused at unraveling the underlying phenomena governing low dimensional systems. Starting with two dimensional electron systems, the group uses novel scan probe techniques that are capable of detecting electric charge with a resolution of 10-4 of one electron and spatial resolution of 100 nm. This technique enables them to image the distribution of electrons and the way they localize in space in various material systems such as GaAs or single monolayers of graphite as well as under various ground state conditions such as the integer and fractional quantum Hall effect. Of particular interest is the 5/2 fractional quantum Hall ground state where the elementary excitations carry a fractional charge of e/4 and obey non-Abelian statistics. Such a system is a model system for topological quantum computation. Reducing dimensionality further to one dimension opens up a fascinating world where electrical conduction is strongly governed by the interaction between electrons. Here the group explores experimentally Luttinger liquid behavior whose strongest manifestation is the separation of spin and charge of the elementary excitations. Finally going down to zero dimensional systems, know as quantum dots, the group studies various approaches to storing and manipulating quantum information using the spin of individual electrons. Most recently, a new approach for nanoscale magnetic field sensing has been developed using a single electron spin in diamond.